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Research Associate

A Pharmaceutical Company is seeking a Research Associate in Frederick, MD. Role Description This role will provide process engineering and analytical support for commercial manufacturing of cell therapy. Working cross functionally with quality, operations, material management, facility and engineering functions, the role is expected to provide technical input for product/process response and investigations, technology implementation, technology transfers, process validation and regulatory filings. • Execute scientific laboratory studies to support process/product understanding and continuous improvement projects • Execute analytical testing of cell therapy products – flow cytometry, ELISA and PCR assays. • Ability to follow laboratory procedures with attention to detail, and successfully execute experiments at the bench • Provide technical input to the execution of process validation and comparability campaigns. • Participate in evaluation of new technology and process automation for introduction into GMP manufacturing • Participate and support process FMEAs to understand process and product risks as a pre-requisite for process validation. • Participate and report to a cross-functional team to advance production activities. • Participate in Operational Excellence activities within Tier Structure. • Participate continuous improvement projects supporting commercial manufacturing site • Ensure systematic DMAIC based approach utilization for process/product related investigations to identify root cause and provide impact assessment to maintain routine manufacturing operations and determine process improvements for manufacturing. • Support technology transfers of launch and commercial cell therapy products • Effectively & efficiently communicate manufacturing process performance internally. • Support the implementation of automation and IT infrastructure projects • Assist in writing technical documentation (protocols & reports for equipment/instrument qualifications, comparability, and cell therapy manufacturing process validation) Skills & Requirements • Bachelors Degree in Biochemical Engineering, Tumor Immunology, Biotechnology or Life Sciences. • Basic understanding in Bioprocessing, Cell Culture and Biochemistry. • Knowledge of ELISA and/or PCR testing • Knowledge in flow cytometry and data analysis (FACSDiva, FlowJo, GraphPad Prism, Excel) is a plus • Ability to think critically, demonstrate troubleshooting and problem-solving skills • Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment • Previous experience with other technologies is a plus • Experience with the use of Microsoft word, Excel, Power Point, Smartsheet, Prism, JMP, and other data analysis applications • Highly collaborative with excellent interpersonal, verbal and written communication skills • Ability to think critically with demonstrated problem-solving and troubleshooting skills • Comfortable working in a fast-paced company environment with minimal direction and able to adjust workload/assignments based upon changing priorities • Self-motivated, detail-oriented, and willing to accept temporary responsibilities outside of initial job description

HAYS PLC • Frederick, U.S.

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Research Associate

A Pharmaceutical Company is seeking a Research Associate in Seattle, WA.Role Description• Design and Develop analytical methods for characterizing on-target and off-target genome modifications in engineered T cells.• Qualify, transfer, validate related analytical methods including training of additional operators• Design and execute experiments as needed including sample testing• Collaborate with others to handle day to day operation of the laboratory to ensure smooth operation.• Maintain accurate and detailed electronic laboratory notebook and author technical and regulatory documents.• Present experimental data in internal or external meetings.Skills & Requirements• B.S. in Molecular Biology or other related biological science disciplines with experience in molecular biology-related studies, or MS in molecular biology or related fields.• Skillful with molecular biology techniques (cloning, construct design, primer/probe design, qPCR, RT-PCR).• Ability to carefully follow existing methods and SOPs and ability to design experiments of higher complexity.• Ability to generate meticulous experimental record, study report, SOP, and other documents.• Strong sense of responsibility, accountability, and integrity.• Strong time management skills with the capacity to prioritize work from multiple projects to meet deadlines.Preferred Qualifications• Working knowledge of electronic laboratory notebook software and DNA analysis software for primer/probe design• Experience with droplet digital PCR (ddPCR)Why Hays?You will be working with a professional recruiter who has intimate knowledge of the Information Technology industry and market trends . Your Hays recruiter will lead you through a thorough screening process in order to understand your skills, experience, needs, and drivers. You will also get support on resume writing, interview tips, and career planning, so when there’s a position you really want, you’re fully prepared to get it.Additionally, this position is a contract role where Hays offers you the opportunity to enroll in full medical, dental or vision benefits.• Medical• Dental• Vision• 401K• Life Insurance ($20,000 benefit)

HAYS PLC • Seattle, Stati Uniti

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Lipid Nanoparticle Scientist

A Pharmaceutical Company is seeking a Lipid Nanoparticle Scientist in San Diego, CA. Role Description The successful candidate will design, manufacture and characterize lipid nanoparticles for the delivery of nucleic acids as well as other novel nanoparticle-based drug delivery formulations containing small molecules, RNA, DNA and proteins. The work is multi-functional and includes formulation design, analytical methods development, physical characterization, experimental design, sample analysis and interpretation of results. The candidate with be expected to bring prior experience in the field and interact closely with other researchers in the design of lipid nanoparticle delivery formulations. This is a hands-on, laboratory-based role in a highly collaborative early development environment. Job Description: • Must have experience with lipid nanoparticle delivery of RNA or DNA for transfection to mammalian cells or in-vivo models. • Must have experience in nanoparticle formulation and nanoparticle drug delivery. • Must have experience in development of methods to analyze and characterize nanoparticle formulations, components and functionality. • Background in the biology of gene transfection and expression is a plus. • Experience and technical proficiency with HPLC and other methods for analysis and quantification of small molecules, DNA and proteins is preferred. • Previous experience and technical proficiency in the physical characterization of nanoparticles, including particle sizing is a plus. • Familiarity with lab-scale nanoparticle preparation techniques, including microfluidics technology, is preferred. • Experience with alternate pharmaceutical manufacturing technologies homogenization, lyophilization, micronization, etc. is a plus. • Strong interpersonal, communication, collaboration and problem solving skills. • Ability to document work and proven record of scientific technical writing. Skills & Requirements • Qualifications: Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, Biomedical Engineering or closely-related discipline with an emphasis in delivery of nucleic acids. M.S. or B.S. in similar fields acceptable with a minimum of 6+ years of relevant industrial experience.

HAYS PLC • San Diego, U.S.

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Molecular Laboratory Technician

Atlas Genomics is a fast-growing molecular diagnostics laboratory located in Seattle, WA. We are seeking an experienced Molecular Laboratory Technician, for our CLIA-regulated high complexity clinical laboratory. We are known for our professional and compassionate service and are looking for someone who shares our values and commitment to providing the highest quality of patient care.Compensation and Work ScheduleCompetitive compensation commensurate to education and experienceSaturday and Sunday; Day or evening shiftDuties and ResponsibilitiesPerform daily, weekly, and monthly equipment maintenance and quality control procedures.Follow the lab procedures for specimen handling, test analysis, reporting, and maintaining records of patient test results.Perform clinical testing on a variety of different specimen types and platforms (to include DNA extraction, PCR techniques and Molecular Sequencing Techniques) in a CLIA-regulated environment, meeting all applicable state and federal guidelines.Perform research studies using various molecular-based techniquesPerform limited Data Entry tasks to include accessioning samples received.Complete other tasks as needed, for laboratory operations.Participate in and implement quality improvement initiativesSupport and initiate activities to ensure ongoing laboratory complianceUphold clinical laboratory best practicesPromote a positive work environment while supporting management and business goalsRequired Education and Experience & Preferred Skills and Qualifications:Required Education: Bachelor's degree in biology, chemistry, genetics or closely related fieldRequired Experience: PCR and/or sequencing experienceMust be eligible to work in the United StatesProficient in reading, writing, speaking and understanding EnglishAwareness of handling biohazardous materials and following established safety guidelinesFamiliarity with laboratory information systems (LIS) and use of Excel filesSelf-motivated and ability to work independently in a high complexity setting.To apply, please submit:Current resume or curriculum vitaeCover letterJob Type: Part-timePay: From $25.00 per hourBenefits:401(k)401(k) matchingDental insuranceHealth insurancePaid time offVision insuranceSchedule:Day shiftWeekend availabilityApplication Question(s):Are you interested in a part-time position working Saturdays and Sundays?Education:Bachelor's (Preferred)Experience:PCR: 1 year (Preferred)License/Certification:MLS License (Preferred)

Glassdoor Inc. • Seattle, Stati Uniti

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Research Entomologist

Job SummaryThe Research Entomologist (Urban Entomology) will work closely with members of the marketing, formulations and regulatory teams to develop new products for an indoor insecticide portfolio. They will be involved in insect rearing and colony maintenance activities for the R&D insectary. They will partner with members of the R&D formulations team to set up and execute insecticidal efficacy trials at our Earth City Laboratory as well as coordinate third party efficacy testing with Contract Research Labs (CROs) and Universities. They will have a strong background in behavior and management of crawling insects, arachnids, and arthropods.Primary Duties & ResponsibilitiesCoordinate third party efficacy testing with CROs and professional pest control networkAnalyze data for claims substantiationGenerate data for new consumer claims or regulatory requirementsInsect rearing and colony maintenanceReview and update procedures vs. federal EPA efficacy guidelinesPrototype and screen efficacy for new product innovationPartner with formulators to recommend and evaluate various active ingredientsMaintain detailed and accurate records of experimental trials, summarize trial results, and assemble study reportsScan competitive activityWork with laboratory personnel to conduct biological efficacy trials that require the handling of insects and insecticides.Support outreach and product education activitiesUS travel to CROs, strategic partners, organized, conferences and meetingsOther duties as assigned.Education and Experience ProfileBachelor’s Degree in Entomology, Biology, or a related science with 3+ years of laboratory experience.Understanding of common urban / structural pest biology.Good Laboratory Practice (GLP) knowledge.Experience in ants, spiders, and common household crawling insects a plus.Experience in product development.Required SkillsDetail oriented.Strong oral and written communication skills.Ability to organize and carry out concurrent projects according to appropriate guidelines and protocols.Ability to work with insects and insecticides on a regular basis in a controlled environment.Ability to collaborate and work effectively with others to achieve results.Work EnvironmentApproximately 80% laboratory/office environment and up to 20% travel

Glassdoor Inc. • Saint Louis, U.S.

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