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IRCCS San Raffaele Scientific Institute in Milan, Italy, is looking for a post-doctoral fellow to join the Biomolecular NMR. The group uses biomolecular NMR spectroscopy coupled to biochemical, biophysical and computational methods to study the structure/function activity of proteins (or protein domains) involved in human diseases (e.g. cancer, genetic diseases) and their interactions with ligands (small molecules, peptides, protein domains).Main activities:acquisition and analysis heteronuclear multidimensional NMR experimentstriple-resonance assignments, interpretation of data for structural calculation, and dynamics studiesacquisition and analysis of ligand based and receptor-based NMR experimentsacquisition and analysis of NMR experiments for metabolomicssupport collaborative projects in drug discovery, structural biology and metabolomicsorganization of NMR timeWho we are looking for:Ph.D in Chemistry, Biochemistry, Physics, Pharmaceutical Chemistry and Technology or equivalentexperience with solution NMR methods in protein structure analysis and/or protein-ligand interactionexperience with Bruker NMR instrumentationability to work independently and assist other team members when necessarygood organizational skills, ability to focus on multiple prioritiesWork details:Type of contract: co.co.coDuration: 1 year, renewablePlace of work: IRCCS San Raffaele Hospital, Via Olgettina, number 60 - Milan (Italy)

Glassdoor Inc. • Milano, Italia

Ref. 190 AJr Research ScientistIRBM, Display Technology Unit (Biophysics)IRBM is a scientific contract research organization (CRO) that stands at the forefront of drug discovery, leveraging a single, unified research facility, located in Pomezia (Rome), Italy, to accelerate team-based breakthroughs and improve efficiencies from initial concept to pre-clinical candidate.With a history of contributing to several approved drugs, and its own internal pipeline of oncology and other therapeutic assets, IRBM is powered by deep collaborations and decades of expertise from leading global institutions. Our comprehensive in-house capabilities assist partners in achieving key milestones and progressing towards clinical readiness, positioning IRBM as a major player in driving innovation in the pharmaceutical and biotech fields.Job DescriptionWe are seeking a passionate and talented scientist to join our Biophysics team in the Display Technologies Unit as a Jr. Research Scientist. The candidate will be involved in the biochemical characterization of biomolecular interactions for biologics, peptides, and small molecules drug discovery. The scientist will work at the bench, under supervision, in an experienced and dynamic team which supports chemists’ and biologists’ work. A high propensity for teamwork, excellent communication skills, proclivity to acquire new competences and proactive attitude are required.Key responsibilitiesDesign and execute experiments to timely reach the objectives under supervision.Accurately record, analyze, summarize, and present data.Perform periodic quality maintenance on instruments and related equipment.Maintain high laboratory standards with regards quality and safetyEstablish productive working relationships with all team members; interact across cross-functional groups.Competencies/SkillsExperience in biochemical or biophysical techniques to study protein/protein or protein/small molecules interactions. Proven knowledge of at least one of the following techniques would be preferred: SPR, BLI, nanoDSF, TSA, ITC and MST.Excellent team orientation and ability to handle multiple projects simultaneously.Strong communication skills, both verbal and written.Outstanding organizational skills.Good knowledge of spoken and written English is mandatory.RequirementsRequired: Master’s degree in Biology, Chemistry, Physics, or related fields with at least 1+ years of relevant research experience.Preferred: proven knowledge of at least one of the following techniques: SPR, BLI, ITC, MSTDuring the job interview we will evaluate candidates’ experience and the job offer will be commensurate.We thank all applicants for their interest, candidates selected for interviews will be contacted.IRBM considers all qualified applicants without discrimination, including on the basis of race, gender, age, disability, gender identity or expression, national origin, religion, sexual orientation, or other protected classes. We nurture an inclusive culture where everyone can show their full potential and enjoy a fulfilling career.

Glassdoor Inc. • Pomezia, Italia