Research Associate /Senior Research Associate – Translational Biology

Autore :


Figura professionale :

Ricercatore o ricercatrice

luogo :

Lexington, U.S.

Tipo di contratto :

Tempo indeterminato

Orario di lavoro :

Tempo pieno

Stipendio :

Retribuzione lorda 80000.00 - 85000.00 $ all'anno

Titolo di studio :

Biologia (laurea triennale)



A Pharmaceutical Company is seeking an Research Associate /Senior Research Associate – Translational Biology in Lexington, MA.

Role Description

• Play a role in guiding creative and rigorous biological research programs aimed at fully understanding the disease mechanism of our pipeline.

• Conduct efficacy, pharmacokinetic, pharmacodynamics, structure-activity-relationship and mechanisms of action studies of drug candidates

• Use appropriate in vivo models to understand the mechanisms by which our drug candidates may contribute to adverse events in patients

• Present working progress to team members in group meeting

• Work closely with members of our research team to develop in vivo strategies to quickly and effectively address key questions related to the safety and efficacy of our drugs.

• Review literature and provide insights to research directions, while predominantly making hands-on contributions to the research

Skills & Requirements

• Bachelor’s or Master’s Degree in Biology, Pharmacology, or related field, with a minimum of 1-3 years of experience.

• Proficient in animal handling, dosing and surgery. Proficient in techniques including but not limited to oral gavage, intravenous injection, subcutaneous injection, blood collection and basic surgery

• In depth knowledge of, and hands-on experience with, in vitro and in vivo models used for mechanistic investigation with small molecule or RNAi therapeutics

• Experience performing molecular and cellular biology techniques, including but not limited to RNA preparation, RT-qPCR, ELISA, immunohistochemistry, urine biomarker analysis, plasma biomarker analysis

• Broad and deep understanding of signaling pathways and biological processes implicated in rare genetic liver diseases as well as the mechanism of action of RNAi therapies is desirable

• Previous experience in drug discovery is preferred

• Outstanding written and oral communication skills

• A high level of motivation and demonstrated record of accomplishment throughout your career

• The ability to work effectively as part of a team, in a fast-paced environment

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