Research Associate /Senior Research Associate – Translational Biology

Éditeur :


Titre d'emploi :

Chercheur ou chercheuse

localisation :

Lexington, U.S.

Type de contrat :

Durée indéterminée

Heures de travail :

Temps plein

Salaire :

Rémunération brute 80000.00 - 85000.00 $ Par an

Titre d'étude :

Biologie (licence)


A Pharmaceutical Company is seeking an Research Associate /Senior Research Associate – Translational Biology in Lexington, MA.

Role Description

• Play a role in guiding creative and rigorous biological research programs aimed at fully understanding the disease mechanism of our pipeline.

• Conduct efficacy, pharmacokinetic, pharmacodynamics, structure-activity-relationship and mechanisms of action studies of drug candidates

• Use appropriate in vivo models to understand the mechanisms by which our drug candidates may contribute to adverse events in patients

• Present working progress to team members in group meeting

• Work closely with members of our research team to develop in vivo strategies to quickly and effectively address key questions related to the safety and efficacy of our drugs.

• Review literature and provide insights to research directions, while predominantly making hands-on contributions to the research

Skills & Requirements

• Bachelor’s or Master’s Degree in Biology, Pharmacology, or related field, with a minimum of 1-3 years of experience.

• Proficient in animal handling, dosing and surgery. Proficient in techniques including but not limited to oral gavage, intravenous injection, subcutaneous injection, blood collection and basic surgery

• In depth knowledge of, and hands-on experience with, in vitro and in vivo models used for mechanistic investigation with small molecule or RNAi therapeutics

• Experience performing molecular and cellular biology techniques, including but not limited to RNA preparation, RT-qPCR, ELISA, immunohistochemistry, urine biomarker analysis, plasma biomarker analysis

• Broad and deep understanding of signaling pathways and biological processes implicated in rare genetic liver diseases as well as the mechanism of action of RNAi therapies is desirable

• Previous experience in drug discovery is preferred

• Outstanding written and oral communication skills

• A high level of motivation and demonstrated record of accomplishment throughout your career

• The ability to work effectively as part of a team, in a fast-paced environment

Cette annonce s'adresse aux deux sexes et aux personnes de tous âges et de toutes nationalités.

Nous vous demandons de lire notre politique de confidentialité disponible sur ce lien